Ethyl Acetate → 3-Acetylamino-6-chloro-2-(4-methoxypyridine-2-carbonyl)indole

HRID 379772Notes

Reaction equation

HRID 379772 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][N:15]=1)=[O:13].[C:22](OCC)(=[O:24])[CH3:23]>>[C:22]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([C:14]1[CH:19]=[C:18]([O:20][CH3:21])[CH:17]=[CH:16][N:15]=1)=[O:13])(=[O:24])[CH3:23]

Participants

3

Reactant 2

HCID 8857Ethyl AcetateHCID 183680323-Amino-6-chloro-2-(4-methoxy-pyridine-2-carbonyl)indole

Product 1

HCID 183679683-Acetylamino-6-chloro-2-(4-methoxypyridine-2-carbonyl)indole

Procedure

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(4-methoxypyridine-2-carbonyl)indole (Example 72). m.p.: 207-208° C. (ethyl acetate)

Sources & evidence

ORD record
ord-390a1854498e4f668c0e703c45e4cd1e
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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