Ethyl Acetate → HCID 18367819, compound

HRID 379783Notes

Reaction equation

[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[CH:9]=2)[N:4]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[C:3]=1[C:19](=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[C:27](OCC)(=[O:29])[CH3:28]>>[C:27]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[CH:9]=2)[N:4]([C:14]([O:16][CH2:17][CH3:18])=[O:15])[C:3]=1[C:19](=[O:26])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)(=[O:29])[CH3:28]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 18367905HCID 18367905, compound

Product 1

HCID 18367819HCID 18367819, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-2-benzoyl-1-(ethoxycarbonyl)-5-nitroindole (step 2). tlc: Rf=0.2 (50% ethyl acetate in hexanes)

Sources & evidence

ORD record: ord-c8ca4cf8df154d7aa11df8204fe6c880
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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