Potassium Bromide → HCID 18367834, compound

HRID 379784Notes

Reaction equation

[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[CH:12]=2)[N:7](C(OCC)=O)[C:6]=1[C:22](=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:3])[CH3:2].[K+].[Br-]>>[C:1]([NH:4][C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([N+:14]([O-:16])=[O:15])[CH:12]=2)[NH:7][C:6]=1[C:22](=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 18367819HCID 18367819, compound

Product 1

HCID 18367834HCID 18367834, compound

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-acetylamino-2-benzoyl-1-(ethoxycarbonyl)-5-nitroindole (step 3). m.p.: 210-212° C. 1H-NMR (CDCl3+CDOD3) δ: 9.14 (1H, d, J=1.8 Hz), 8.19 (1H, dd, J=2.6, 9.2 Hz), 7.84 (1H, d, J=8.8 Hz), 7.4-7.8 (5H, m), 2.20 (3H, s) IR (KBr) ν: 1665, 1620, 1435, 1345, 1265, 1020, 915, 820 cm−1

Sources & evidence

ORD record: ord-a0575f5a2ccf438d8c2b51fe5211c93c
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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