Isovaleryl chloride → 2-(3-Chlorobenzoyl)-3-(isovalerylamino)-5-nitroindole

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 19 employing 3-amino-2-(3-chlorobenzoyl)-5-nitroindole (step 2) and isovaleryl chloride. m.p.: 197-199° C. 1H-NMR (CDCl3) δ: 9.91 (1H, br s), 9.37 (1H, d, J=2.2 Hz), 8.73 (1H, br.s), 8.24 (1H, dd, J=2.2, 9.2 Hz), 7.51-7.80 (4H, m), 7.38 (1H, d, J=9.2 Hz),2.37 (2H, br.s), 2.24-2.29 (1H, m), 1.07 (3H, s), 1.05 (3H, s)

Provenance & Evidence