2-Bromo-1-(3-methylphenyl)ethan-1-one → HCID 18368201, compound

HRID 379788Notes

Reaction equation

HRID 379788 reaction equation
[CH2:1]([O:3][C:4]([NH:6][C:7]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][C:8]=1[C:9]#[N:10])=[O:5])[CH3:2].Br[CH2:19][C:20]([C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH3:28])[CH:23]=1)=[O:21]>C(OCC)(=O)C>[NH2:10][C:9]1[C:8]2[C:7](=[CH:14][CH:13]=[C:12]([N+:15]([O-:17])=[O:16])[CH:11]=2)[N:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])[C:19]=1[C:20](=[O:21])[C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH3:28])[CH:23]=1

Participants

4

Reactant 2

HCID 100361292-Bromo-1-(3-methylphenyl)ethan-1-oneHCID 183679462-(Ethoxycarbonylamino)-5-nitrobenzonitrile

Product 1

HCID 18368201HCID 18368201, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The title compound was prepared according to the procedure described in step 2 of Example 1 from 2-(ethoxycarbonylarnino)-5-nitrobenzonitrile (Example 96, step 1) and 2-bromo-3′-methylacetophenone. tlc: Rf=0.6 (33% ethyl acetate in hexanes)

Sources & evidence

ORD record
ord-00f8cf3fc0d64fb380f68bfd594307d8
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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