HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 18367819, compound → HCID 18367823, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 18367819 | HCID 18367819 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 18367823 | HCID 18367823 | — |
Reaction Steps
3-Acetylamino-2-benzoyl-1-(ethoxycarbonyl)-5-nitroindole (Example 96, step 3; 200 mg, 0.51 mmol) was hydrogenolyzed in the presence of palladium on activated carbon (5%, 50 mg) in ethyl acetate (40 ml) at atmospheric pressure for 4 h. Catalyst was removed by filtration and the filtrate was concentrated to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300363B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-b9cafbbd401744a6bd4a339c7690eff0 |
| Source note | uspto-grants-2001_10 |