Ethyl Acetate → HCID 18368128, compound

HRID 379792Notes

Reaction equation

[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:14]([F:17])([F:16])[F:15])=[CH:8][C:9]=2[N+]([O-])=O)[N:4]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:3]=1[C:23](=[O:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1.[C:31](OCC)(=[O:33])[CH3:32]>>[C:31]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:14]([F:15])([F:16])[F:17])=[CH:8][CH:9]=2)[N:4]([C:18]([O:20][CH2:21][CH3:22])=[O:19])[C:3]=1[C:23](=[O:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)(=[O:33])[CH3:32]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 18368137HCID 18368137, compound

Product 1

HCID 18368128HCID 18368128, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-2-benzoyl-1-(ethoxycarbonyl)-6-trifluoromethylnitroindole (step 2). tlc: Rf=0.6 (50% ethyl acetate in hexanes)

Sources & evidence

ORD record: ord-0279fb2c2a4b4351a7a0c618cca5ee81
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

Loading…