Ethyl Acetate → HCID 18367761, compound

HRID 379793Notes

Reaction equation

[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Br:11])[CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17](=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:25](OCC)(=[O:27])[CH3:26]>>[C:25]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([Br:11])[CH:9]=2)[N:4]([C:12]([O:14][CH2:15][CH3:16])=[O:13])[C:3]=1[C:17](=[O:24])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1)(=[O:27])[CH3:26]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 18367855HCID 18367855, compound

Product 1

HCID 18367761HCID 18367761, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-2-benzoyl-5-bromo-1-(ethoxycarbonyl)indole (step 2). tlc: Rf=0.3 (33% ethyl acetate in hexanes)

Sources & evidence

ORD record: ord-72c3546aa48a4284b6dcc6d5119aaec2
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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