Ethyl Acetate → HCID 18367774, compound

HRID 379808Notes

Reaction equation

[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]#[N:12])=[CH:8][CH:9]=2)[N:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:3]=1[C:18](=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[C:26](OCC)(=[O:28])[CH3:27]>>[C:26]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([C:11]#[N:12])=[CH:8][CH:9]=2)[N:4]([C:13]([O:15][CH2:16][CH3:17])=[O:14])[C:3]=1[C:18](=[O:25])[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)(=[O:28])[CH3:27]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 18367744HCID 18367744, compound

Product 1

HCID 18367774HCID 18367774, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-2-benzoyl-6-cyano-1-(ethoxycarbonyl)indole (step 2). tlc: Rf=0.1 (33% ethyl acetate in hexanes)

Sources & evidence

ORD record: ord-a6c66814a8b949778b70021db9bbf972
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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