Acetyl chloride → HCID 18368130, compound
Reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12](=[O:23])[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([O:21][CH3:22])=[O:20])[CH:14]=1.[C:24](Cl)(=[O:26])[CH3:25]>C(OCC)(=O)C>[C:24]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12](=[O:23])[C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([O:21][CH3:22])=[O:20])[CH:14]=1)(=[O:26])[CH3:25]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The title compound was prepared according to the procedure described in Example 19 employing 3-amino-6-chloro-2-(3-methoxycarbonylbenzoyl)indole (Example 133) and acetyl chloride. m.p.: 190-193° C. (ethyl acetate)
Sources & evidence
- ORD record
- ord-d86bdfb5cdcc47aaa6b025724feeeec9
- Source dataset
- uspto-grants-2001_10
- Patent number
- US06300363B1
Reaction notes
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