Acetyl chloride → 3-Acetylamino-6-chloro-1-(ethoxycarbonyl)-2-(3-nitrobenzoyl)indole

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 2 (Method A) from 3-amino-6-chloro-1-ethoxycarbonyl-2-(3-nitrobenzoyl)indole (step 1) and acetyl chloride. 1H-NMR (CDCl3) δ: 9.18 (1H, br s), 8.65-8.69 (1H, m), 8.38-8.42 (1H, m), 8.02-8.10 (1H, m), 7.98 (1H, s), 7.61-7.71 (2H, m), 7.18-7.25 (1H, m), 4.15 (2H, q, J=7.0 Hz), 2.24 (3H, s), 1.17 (3H, t, J=7.0 Hz)

Provenance & Evidence