Acetyl chloride → 3-(3-Acetylamino-6-chloroindole-2-carbonyl)benzenesulfonamide

HRID 379845Notes

Reaction equation

HRID 379845 reaction equation
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([C:14]1[CH:15]=[C:16]([S:20]([NH2:23])(=[O:22])=[O:21])[CH:17]=[CH:18][CH:19]=1)=[O:13].[C:24](Cl)(=[O:26])[CH3:25]>C(O)C.C1(C)C=CC=CC=1>[C:24]([NH:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[NH:4][C:3]=1[C:12]([C:14]1[CH:15]=[C:16]([S:20]([NH2:23])(=[O:21])=[O:22])[CH:17]=[CH:18][CH:19]=1)=[O:13])(=[O:26])[CH3:25]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 183677953-(3-Amino-6-chloroindole-2-carbonyl)benzenesulfonamide

Product 1

HCID 183679243-(3-Acetylamino-6-chloroindole-2-carbonyl)benzenesulfonamide

Reagents, catalysts & solvents 1

HCID 21863594Toluene ethanolSolvent

Procedure

The title compound was prepared according to the procedure described in Example 19 employing 3-(3-amino-6-chloroindole-2-carbonyl)benzenesulfonamide (Example 142) and acetyl chloride. m.p.: 250-251° C. (ethanol/toluene)

Sources & evidence

ORD record
ord-b6809f1122ca4058852d5e01f0c15d37
Source dataset
uspto-grants-2001_10
Patent number
US06300363B1

Reaction notes

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