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HRID379853

反应详情

EQUATION

反应方程式

HRID 379853 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)n1c(C(=O)c2ccccc2)c(N(CC(=O)OC)C(C)=O)c2ccc(Cl)cc21
HCID18368158

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)N(CC(=O)O)c1c(C(=O)c2ccccc2)[nH]c2cc(Cl)ccc12
HCID18367940

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The title compound was prepared according to the procedure described in step 2 of Example 2 (Method A) from 3-(N-acetyl-N-methoxycarbonylmethylamino)-2-benzoyl-6-chloro-1-(ethoxycarbonyl)indole (step 1). m.p.: 148-154° C. (dichloromethane) 1H-NMR (DMSO-d6) δ: 12.53 (1H, br s), 12.17 (1H, br s), 7.85 (1H, d, J=8.8 Hz), 7.78-7.62 (3H, m), 7.62-7.51 (3H, m), 7.22 (1H, dd, J=1.8, 8.8 Hz), 3.96 (1H, d, J=17.2 Hz), 3.66 (1H, d, J=17.2 Hz), 1.80 (s, 3H)