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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 379888Generated: October 25, 2026

4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrile → 2-(4-Acetoxymethyl-2-furoyl)-3-amino-6-chloro-1-(ethoxycarbonyl)indole

https://huagongshe.com/reaction/379888

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-[(ethoxycarbonyl)amino]benzonitrileHCID 18367888—
Reactant4-Acetoxymethyl-2-(bromoacetyl)furanHCID 18367908—
Product2-(4-Acetoxymethyl-2-furoyl)-3-amino-6-chloro-1-(ethoxycarbonyl)indoleHCID 18367907—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 1 employing 4-chloro-2-(ethoxycabonylamino)benzonitrile (Exampe 1, step 1) and 4-acetoxymethyl-2-(bromoacetyl)furan (step 1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06300363B1
Source datasetuspto-grants-2001_10
ORD IDord-7881e9318475489ba2ea17f773ae17b8
Source noteuspto-grants-2001_10