Isobutyryl chloride → HCID 18367949, compound

HRID 379900Notes

Reaction equation

[C:1]([O:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][C:7]=1[C:11]([C:13]1[N:14]([C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:15]2[C:20]([C:21]=1[NH2:22])=[CH:19][CH:18]=[C:17]([Cl:23])[CH:16]=2)=[O:12])(=[O:3])[CH3:2].[C:29](Cl)(=[O:33])[CH:30]([CH3:32])[CH3:31]>>[C:1]([O:4][CH2:5][C:6]1[CH:10]=[CH:9][O:8][C:7]=1[C:11]([C:13]1[N:14]([C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:15]2[C:20]([C:21]=1[NH:22][C:29](=[O:33])[CH:30]([CH3:32])[CH3:31])=[CH:19][CH:18]=[C:17]([Cl:23])[CH:16]=2)=[O:12])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 62325Isobutyryl chloride

HCID 18368153HCID 18368153, compound

Product 1

HCID 18367949HCID 18367949, compound

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 2 employing 2-(3-acetoxymethyl-2-furoyl)-3-amino-6-chloro-1-(ethoxycarbonyl)indole (step 1) and isobutyryl chloride.

Sources & evidence

ORD record: ord-982797bf5a20462789d625c7e3bdb798
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06300363B1

Reaction notes

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