N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)propan-1-amine → (1E,4E)-2-amino-N-(2,3-dihydroxypropyl)-N-propyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)propan-1-amine	HCID 57577780	—
Edukt	(1E,4E)-2-(tert-butoxycarbonylamino)-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxylic acid	HCID 66960164	—
Produkt	(1E,4E)-2-amino-N-(2,3-dihydroxypropyl)-N-propyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide	HCID 51033629	—

Reaktionsschritte

The title compound was prepared by the procedures as described in Example 101 (Step H and I) using (1E,4E)-2-(tert-butoxycarbonylamino)-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxylic acid and N-((2,2-dimethyl-1,3-dioxolan-4-yl)methyl)propan-1-amine.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08524702B2
Quelldatensatz	uspto-grants-2013_09
ORD ID	ord-3d8f8b7754984a908a0d1df78fe26999
Quellennotiz	uspto-grants-2013_09