1-Pyrrolidineethanamine → HCID 18367625, compound

HRID 379984Notes

Reaction equation

HRID 379984 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:8][CH2:7][CH2:6][CH2:5]1.[Br:9][C:10]1[CH:11]=[C:12]([S:16]([Cl:19])(=[O:18])=[O:17])[CH:13]=[CH:14][CH:15]=1>C(OCC)C>[ClH:19].[Br:9][C:10]1[CH:11]=[C:12]([S:16]([NH:1][CH2:2][CH2:3][N:4]2[CH2:8][CH2:7][CH2:6][CH2:5]2)(=[O:18])=[O:17])[CH:13]=[CH:14][CH:15]=1

Participants

4

Reactant 2

HCID 13441-PyrrolidineethanamineHCID 17943m-Bromobenzenesulphonyl chloride

Product 1

HCID 18367625HCID 18367625, compoundYield 85.9%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

N-(2-Aminoethyl)pyrrolidine (1.61 g) was added dropwise to a solution of 3-bromobenzenesulfonyl chloride (3.61 g) in diethyl ether (100 ml) at room temperature. The resulting suspension was stirred for 30 minutes and filtered to afford the sub-title compound as a solid (4.48 g).

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-dfe8c2c8deca40068cde13aa562b8032
Source dataset
uspto-grants-2001_10
Patent number
US06300352B1

Reaction notes

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