2-Bromopyridine → 2-Nitro-4-(2-pyridinyl)benzaldehyde

HRID 38011Notes

Reaction equation

HRID 38011 reaction equation
[N+:1]([C:4]1[CH:11]=[C:10](B2OC(C)(C)C(C)(C)O2)[CH:9]=[CH:8][C:5]=1[CH:6]=[O:7])([O-:3])=[O:2].Br[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=1>O1CCOCC1>[N+:1]([C:4]1[CH:11]=[C:10]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][N:23]=2)[CH:9]=[CH:8][C:5]=1[CH:6]=[O:7])([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 79732-BromopyridineHCID 754875122-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde

Product 1

HCID 866534802-Nitro-4-(2-pyridinyl)benzaldehyde

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

The title compound was prepared by the procedure as described in Example 101 (Step C) using 2-nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde and 2-bromopyridine in dioxane (reflux).

Sources & evidence

ORD record
ord-7748fb0ae7824eeb97b2dcf13b52c054
Source dataset
uspto-grants-2013_09
Patent number
US08524702B2

Reaction notes

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