HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine → (2R)-2-(4,5-diphenyloxazol-2-yl)pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine | HCID 54511676 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2R)-2-(4,5-diphenyloxazol-2-yl)pyrrolidine | HCID 15505347 | — |
Reaction Steps
A mixture of (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine (4 g) and 10% Pd/C (0.5 g) in ethanol (120 ml) was stirred under H2 for 10 hours. The catalyst was filtered off and filtrate was evaporated in vacuo to give (2R)-2-(4,5-diphenyloxazol-2-yl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06300344B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-37e8f712b77144a8a1a95c27c1ae8b24 |
| Source note | uspto-grants-2001_10 |