反应详情

3-Chloro-4-cyclobutyl-6-hydrazinopyridazine (0.50 g, 2.5 mmol) and 4-hydroxybenzaldehyde (0.31 g, 2.5 mmol) were stirred in 0.2M hydrochloric acid (15 ml) for 2 hours. The precipitated imine was then collected by filtration and dried to give the title compound (0.63 g, 83%). MS (ES+) 305 [MH]+, 303 [MH]+.

1. filtrationThe precipitated imine was then collected by filtration
2. customdried