HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 4-(6-Chloro-5-cyclobutylpyridazin-3-ylhydrazonomethyl)phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | 3-chloro-4-cyclobutyl-6-hydrazinylPyridazine | HCID 22609946 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(6-Chloro-5-cyclobutylpyridazin-3-ylhydrazonomethyl)phenol | HCID 136446230 | 83.2% |
Reaction Steps
3-Chloro-4-cyclobutyl-6-hydrazinopyridazine (0.50 g, 2.5 mmol) and 4-hydroxybenzaldehyde (0.31 g, 2.5 mmol) were stirred in 0.2M hydrochloric acid (15 ml) for 2 hours. The precipitated imine was then collected by filtration and dried to give the title compound (0.63 g, 83%). MS (ES+) 305 [MH]+, 303 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303605B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-d5e2d2bf4a10470cb3ed25df16076038 |
| Source note | uspto-grants-2001_10 |