HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Phenylpiperidine → 4-(4-Fluorophenyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Phenylpiperidine | HCID 69873 | — |
| Reactant | 4-(4-Fluorophenyl)piperidine | HCID 2759136 | — |
| Reactant | 1-Benzyl-3-(SR)-formyl-4-(RS)-(3-thienyl)pyrrolidine | HCID 18364719 | — |
| Product | 4-(4-Fluorophenyl)piperidine | HCID 2759136 | — |
| Product | 1-Benzyl-3-(RS)-(4-(4-fluorophenyl)piperidinylmethyl)-4-(RS)-(3-thienyl)pyrrolidine | HCID 18364739 | — |
Reaction Steps
The title compound was prepared from 1-benzyl-3-(SR)-formyl-4-(RS)-(3-thienyl)pyrrolidine and 4-(4-fluorophenyl)piperidine according to procedures described in Example 1. 4-(4-fluorophenyl)piperidine was prepared according to procedures used to prepare 4-phenylpiperidine in Example 1. Mass Spectrum (CI) m/e 435 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06303593B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-cd7ff1e7caeb485aa6cb7e6a5e5d2108 |
| Source note | uspto-grants-2001_10 |