HRID381198

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1

HCID4917

Prochlorperazine

C20H24ClN3S

结构：OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

HCID6251

未命名化合物

结构：CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]

HCID11177

Magnesium stearate

C36H70MgO4

PRODUCTS

生成物

结构：CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1.CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3

HCID9852396

未命名化合物

PROCEDURE

实验过程

Separately, prochlorperazine was added to and blended with the mannitol (Part B). Parts A and B were then combined and mixed for about 5 minutes in a V-shaped blender. Next, magnesium stearate was added to the blender, followed by continued blending for about 2 minutes.

WORKUP

后处理

additionmixed for about 5 minutes in a V-shaped blender

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-acae6ebb88f84ece86b596f4d4674f55
来源数据集: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06306437B1
来源说明: uspto-grants-2001_10

反应 SMILES

[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:20]3[CH:21]=[C:22]([Cl:25])[CH:23]=[CH:24][C:19]=3[S:18][C:17]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]2=3)[CH2:4][CH2:3]1.[CH2:26]([OH:37])[C@H:27]([C@H:29]([C@@H:31]([C@@H](CO)O)O)O)[OH:28].C([O-])(=O)CCCCCCCCCCCCCCCCC.[Mg+2].C([O-])(=O)CCCCCCCCCCCCCCCCC>>[CH3:10][N:11]1[C@@H:12]2[CH2:17][C:16]3[CH:31]=[CH:29][C:27]([OH:28])=[C:26]([OH:37])[C:15]=3[C:14]3[C:13]2=[C:22]([CH:23]=[CH:24][CH:19]=3)[CH2:21][CH2:20]1.[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][CH2:10][N:11]2[C:20]3[CH:21]=[C:22]([Cl:25])[CH:23]=[CH:24][C:19]=3[S:18][C:17]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]2=3)[CH2:4][CH2:3]1