Diisopropyl Ether → HCID 22467253, compound

HRID 381332Notes

Reaction equation

[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH:11]([C:16]3[C:24]([Cl:25])=[CH:23][C:19]4[O:20][CH2:21][O:22][C:18]=4[CH:17]=3)[C:12]([O:14][CH3:15])=[O:13])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.[CH:26](OC(C)C)(C)C>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([CH:11]([C:16]3[C:24]([Cl:25])=[CH:23][C:19]4[O:20][CH2:21][O:22][C:18]=4[CH:17]=3)[C:12]([O:14][CH3:15])=[O:13])=[CH:7][N:8]2[CH3:26])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7914Diisopropyl Ether

HCID 22467203HCID 22467203, compound

Product 1

HCID 22467253HCID 22467253, compound

Procedure

The subtitle compound was prepared following the procedure of Example 92(d), using methyl 2-(6-bromo-1H-3-indolyl)-2-(6-chloro-1,3-benzodioxol-5-yl)acetate from step (c), m.p. 183-185° C., from diisopropyl ether.

Sources & evidence

ORD record: ord-c0770296b75343b7be6a4d708d74ed82
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06306852B1

Reaction notes

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