Phenylacetic Acid → HCID 86757515, compound

HRID 381403Notes

Reaction equation

HRID 381403 reaction equation
[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([C:6]([N:8]2[C:16]3[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=3)[CH:10]=[C:9]2[CH3:19])=[O:7])=[CH:4][CH:3]=1.[CH2:22]([C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][C:32]=1Cl)[C:27](N)=O)[CH3:23].COC1C=C2C(=CC=1)[NH:41][C:40](C)=C2CCN.C1(CC(O)=O)C=CC=CC=1>>[Cl:1][C:2]1[CH:21]=[CH:20][C:5]([C:6]([N:8]2[C:16]3[C:11](=[CH:12][C:13]([O:17][CH3:18])=[CH:14][CH:15]=3)[CH:10]=[C:9]2[CH3:19])=[O:7])=[CH:4][CH:3]=1.[CH2:22]([C:24]1[CH:25]=[C:26]([CH2:27][CH2:40][NH-:41])[CH:30]=[CH:31][CH:32]=1)[CH3:23]

Participants

4

Reactant 3

HCID 999Phenylacetic AcidHCID 528992-(5-Methoxy-2-methyl-1H-indol-3-yl)ethanamineHCID 69379171HCID 69379171, compound

Product 1

HCID 86757515HCID 86757515, compound

Procedure

The procedure employed for preparation of Compound 9e was repeated except as follows. In the treatment of Compound 7, phenylacetic acid was used instead of 4-chlorobenzoic acid, so the resultant was 8i instead of 8e.

Sources & evidence

ORD record
ord-c611f87a5a4f49498168445b6f2d790c
Source dataset
uspto-grants-2001_10
Patent number
US06306890B1

Reaction notes

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