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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 381413Generated: October 29, 2026

1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)- → HCID 178462383, compound

https://huagongshe.com/reaction/381413

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole, (2R-cis)-HCID 10131191—
ReactantHCID 178477147HCID 178477147—
ProductHCID 178462383HCID 17846238359%

Reaction Steps

Reaction was carried out in the same manner as in Example 1 using (2R,3S)-2-(2,4-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane and trans-1-(acetylthio)-4-[(1E,3E)-4-[4-(trifluoromethyl)phenyl]-1,3-butadien-1-yl]cyclohexane as described in Reference example 43 to obtain the title compound having a melting point of 74 to 76° C. in a yield of 59%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06306880B1
Source datasetuspto-grants-2001_10
ORD IDord-d8584ff49d4d4d6b841f5b7cc28cbb73
Source noteuspto-grants-2001_10