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HRID381648

反应详情

EQUATION

反应方程式

HRID 381648 的结构方程式

REACTANTS

反应物

3
结构：C[N+]1(CCN=C=NC2CCCCC2)CCOCC1.Cc1ccc(S(=O)(=O)[O-])cc1
HCID17220

4-(2-{[(Cyclohexylimino)methylidene]amino}ethyl)-4-methylmorpholin-4-ium 4-methylbenzene-1-sulfonate

C21H33N3O4S

结构：CC(C)N=C=S
HCID75263

Isopropyl isothiocyanate

C4H7NS

结构：Nc1ccc(Cl)c(Cl)c1N
HCID10845020

3,4-dichloro-1,2-phenylenediamine

C6H6Cl2N2

PRODUCTS

生成物

1
结构：CC(C)Nc1nc2cc(Cl)c(Cl)cc2[nH]1
HCID22995418

5,6-Dichloro-N-(propan-2-yl)-1H-benzimidazol-2-amine

C10H11Cl2N3

收率 67%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

5,6-Dichloro-1,2-phenylenediamine (200.0 g, 1.13 mol), isopropyl isothiocyanate (122.0 g, 1.21 mol), 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate (622.0 g, 1.47 mol) and pyridine (4 L) were used according to general procedure I. The product was recrystallized from acetonitrile to give 184 g (67%) of a brown solid. Analytical data were consistent with those reported above.

WORKUP

后处理

  1. customThe product was recrystallized from acetonitrile