HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-((4-Chlorophenyl)(4-piperidinyloxy)methyl)pyridine → 2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine, (S)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-((4-Chlorophenyl)(4-piperidinyloxy)methyl)pyridine | HCID 11141197 | — |
| Reactant | (2R,3R)-2-hydroxy-3-(4-methoxyphenyl)-3-(2-nitrophenylthio)propionic acid | HCID 13191817 | — |
| Product | 2-((4-Chlorophenyl)(piperidin-4-yloxy)methyl)pyridine, (S)- | HCID 10892005 | — |
Reaction Steps
By treating (±)-4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidine and (2R,3R)-2-hydroxy-3-(4-methoxy-phenyl)-3-(2-nitrophenylthio)propionic acid in the same manner as in Example 4-(1), (2) and (3) to afford (S)-4-[(4-chlorophenyl) (2-pyridyl)methoxy]piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06307052B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-d3e7310ba2b74530ba97ab5257c82fcb |
| Source note | uspto-grants-2001_10 |