反应详情

In a manner similar to Example 4, Step (b), 4-(4′-methyl-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.21 g, 0.0043 mol) was refluxed in 6 M aqueous hydrochloric acid to give 1.12 g of 4-(4′-methyl-biphenyl-4-yl)-4-oxo-butyric acid as an off-white solid; mp 183-186° C.