反应详情

In a manner similar to Example 4, Step (b), 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.360 g, 0.004033 mol) was refluxed in 6 M aqueous hydrochloric acid (25 mL) to give 1.280 g of 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid as a white solid; mp 154-156° C.