Hydrogen Bromide → HCID 135709021, compound

Participants

Reaction Conditions

Reaction Steps

1.00 g (3.01 mmol) of 7-benzyl-2-(3-methoxyphenyl)hypoxanthine prepared according to the same method as in Example 16 was dissolved in 20 ml of acetic acid. 3 ml of hydrobromic acid was added to the solution, followed by stirring for 35.5 hours at 100° C. Crystals obtained by cooling was separated by filtration and washed with distilled water and ethanol. The resulting crude crystals were purified by recrystallization from ethanol to obtain 0.64 g of 7-benzyl-2-(3-hydroxyphenyl)hypoxanthine (yield 67%).

Provenance & Evidence