Hydrogen Bromide → HCID 135709029, compound

Participants

Reaction Conditions

Reaction Steps

1.36 g (4.09 mmol) of 7-benzyl-2-(2-methoxyphenyl) hypoxanthine prepared by the same method as in Example 15 was dissolved in 20 ml of acetic acid. After the addition of 3 ml of hydrobromic acid, the mixture was stirred for 35.5 hours at 100° C. After cooling, the produced crystals were separated by filtration and washed with distilled water and ethanol. The crude crystals were purified by suspension in hot ethanol to obtain 0.88 g of 7-benzyl-2-(2-hydroxyphenyl)hypoxanthine (yield 68%).

Provenance & Evidence