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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382394Generated: November 1, 2026

Benzoyl chloride → HCID 18360158, compound

https://huagongshe.com/reaction/382394

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chlorideHCID 7412—
Reactant3-(Trifluoromethyl)benzoyl chlorideHCID 75257—
Reactant1-benzyl-4-amino-1H-imidazole-5-carboxamideHCID 14000620—
ProductHCID 18360158HCID 1836015892%

Reaction Steps

out under the same conditions as in Example 1, using 2.16 g (9.99 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide which was prepared in the same manner as in Reference Example 2 and 3-trifluoromethylbenzoyl chloride, instead of benzoyl chloride, to obtain 3.56 g 1-benzyl-4-(3-trifluoromethylbenzoylamino)-5-imidazolecarboxamide (yield 92%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310070B1
Source datasetuspto-grants-2001_10
ORD IDord-fc12c323892d4d0f896941d5959bea00
Source noteuspto-grants-2001_10