HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nicotinic Acid → HCID 18360567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nicotinic Acid | HCID 938 | — |
| Reactant | HCID 18360275 | HCID 18360275 | — |
| Product | HCID 18360567 | HCID 18360567 | 79% |
Reaction Steps
An amidation reaction and post-treatment were carried out under the same conditions as in Example 19, using 1.50 g (6.38 mmol) of 4-amino-1-(4-fluorobenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 58 and nicotinic acid instead of cyclopentylacetic acid to obtain 1.70 g of 1-(4-fluorobenzyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-bd860dd0b9da4598b8f299cea8dbc843 |
| Source note | uspto-grants-2001_10 |