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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382399Generated: October 31, 2026

Nicotinic Acid → HCID 18360567, compound

https://huagongshe.com/reaction/382399

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinic AcidHCID 938—
ReactantHCID 18360275HCID 18360275—
ProductHCID 18360567HCID 1836056779%

Reaction Steps

An amidation reaction and post-treatment were carried out under the same conditions as in Example 19, using 1.50 g (6.38 mmol) of 4-amino-1-(4-fluorobenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 58 and nicotinic acid instead of cyclopentylacetic acid to obtain 1.70 g of 1-(4-fluorobenzyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 79%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310070B1
Source datasetuspto-grants-2001_10
ORD IDord-bd860dd0b9da4598b8f299cea8dbc843
Source noteuspto-grants-2001_10