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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382400Generated: November 1, 2026

Nicotinic Acid → HCID 18360507, compound

https://huagongshe.com/reaction/382400

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinic AcidHCID 938—
ReactantHCID 18360350HCID 18360350—
ProductHCID 18360507HCID 1836050778%

Reaction Steps

An amidation reaction and post-treatment were carried out under the same conditions as in Example 19, using 1.50 g (5.98 mmol) of 4-amino-1-(3-chlorobenzyl)-5-imidazole carboxamide which was prepared in the same manner as in Example 51 and nicotinic acid instead of cyclopentylacetic acid to obtain 1.65 g of 1-(3-chlorobenzyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 78%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310070B1
Source datasetuspto-grants-2001_10
ORD IDord-85aa6b82f08842678c3504f5c406c375
Source noteuspto-grants-2001_10