2-Fluorobenzoyl chloride → HCID 18360329, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 1, using 1.97 g (8.00 mmol) of 4-amino-1-(3-methoxybenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 81 and 2-fluorobenzoyl chloride instead of benzoyl chloride to obtain 2.42 g of 4-(2-fluorobenzoylamino)-1-(3-methoxybenzyl)-5-imidazole carboxamide (yield 82%).

Provenance & Evidence