Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → HCID 18360169, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 1.97 g (8.00 mmol) of 4-amino-1-(3-methoxybenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 81 and 2-(N-t-butyloxycarbonyl-N-methylamino)acetic acid instead of 3-pyridylacetic acid hydrochloride to obtain 2.12 g of 4-(2-(N-t-butyloxycarbonyl-N-methylamino)acetylamino)-1-(3-methoxybenzyl)-5-imidazolecarboxamide (yield 63%).

Provenance & Evidence