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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382410Generated: November 1, 2026

Nicotinic Acid → HCID 18360418, compound

https://huagongshe.com/reaction/382410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNicotinic AcidHCID 938—
ReactantHCID 18360432HCID 18360432—
ProductHCID 18360418HCID 18360418—

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 2.00 g (8.69 mmol) of 4-amino-1-(2-phenylethyl)-5-imidazolecarboxamide prepared in the same manner as in Example 56 and nicotinic acid instead of 3-pyridylacetic acid hydrochloride to obtain crude 1-(2-phenylethyl)-4-(3-pyridylcarbonylamino)-5-imidazolecarboxamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310070B1
Source datasetuspto-grants-2001_10
ORD IDord-d7e6a73893c642d0b6f860b088a3d58a
Source noteuspto-grants-2001_10