HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Thiophenecarboxylic acid → HCID 18360530, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Thiophenecarboxylic acid | HCID 10700 | — |
| Reactant | 1-benzyl-4-amino-1H-imidazole-5-carboxamide | HCID 14000620 | — |
| Product | HCID 18360530 | HCID 18360530 | 60% |
Reaction Steps
An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 2.14 g (9.99 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide prepared in the same manner as in Reference Example 2 and 2-thiophenecarboxylic acid instead of 3-pyridylacetic acid hydrochloride to obtain 1.97 g of 1-benzyl-4-(2-thienylcarbonylamino)-5-imidazolecarboxamide (yield 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-912513d0973b49d18120b336c9aabcc3 |
| Source note | uspto-grants-2001_10 |