HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzoyl chloride → HCID 18360380, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| Reactant | 4-Amino-1-(4-methylbenzyl)-5-imidazolecarboxamide | HCID 18360569 | — |
| Product | HCID 18360380 | HCID 18360380 | 88% |
Reaction Steps
An amidation reaction and post-treatment were carried out following the conditions of Example 1, using 2.30 g (9.99 mmol) of 4-amino-1-(4-methylbenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 87 and 3-fluorobenzoyl chloride instead of benzoyl chloride to obtain 3.11 g of 4-(3-fluorobenzoylamino)-1-(4-methylbenzyl)-5-imidazole carboxamide (yield 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-68153e3e9d2b4a2db5a51af0917b2a13 |
| Source note | uspto-grants-2001_10 |