HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoyl chloride → HCID 18360516, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | 4-Amino-1-(4-methylbenzyl)-5-imidazolecarboxamide | HCID 18360569 | — |
| Product | HCID 18360516 | HCID 18360516 | 64% |
Reaction Steps
An amidation reaction and post-treatment were carried out following the conditions of Example 1, using 2.30 g (9.99 mmol) of 4-amino-1-(4-methylbenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 87 and 4-fluorobenzoyl chloride instead of benzoyl chloride to obtain 2.26 g of 4-(4-fluorobenzoylamino)-1-(4-methylbenzyl)-5-imidazole carboxamide (yield 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-929fea50df074edba5bb553f6f457733 |
| Source note | uspto-grants-2001_10 |