HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isonicotinic Acid → 1-Benzyl-4-(4-pyridylcarbonylamino)-5-imidazolecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isonicotinic Acid | HCID 5922 | — |
| Reactant | 1-benzyl-4-amino-1H-imidazole-5-carboxamide | HCID 14000620 | — |
| Product | 1-Benzyl-4-(4-pyridylcarbonylamino)-5-imidazolecarboxamide | HCID 18360257 | 78% |
Reaction Steps
An amidation reaction and post-treatment were carried out following the conditions of Example 19, using 1.00 g (4.62 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide prepared in the same manner as in Reference Example 2 and isonicotinic acid instead of cyclopentylacetic acid to obtain 1.16 g of 1-benzyl-4-(4-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-6d299c58b2a74678a2e81299fb56da18 |
| Source note | uspto-grants-2001_10 |