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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382431Generated: November 1, 2026

Isonicotinic Acid → HCID 18360438, compound

https://huagongshe.com/reaction/382431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsonicotinic AcidHCID 5922—
ReactantHCID 18360275HCID 18360275—
ProductHCID 18360438HCID 1836043865%

Reaction Steps

An amidation reaction and post-treatment were carried out under the same conditions as in Example 19, using 2.0 g (8.5 mmol) of 4-amino-1-(4-fluorobenzyl)-5-imidazolecarboxamide which was prepared in the same manner as in Example 58 and isonicotinic acid instead of cyclopentylacetic acid to obtain 1.87 g of 1-(4-fluorobenzyl)-4-(4-pyridylcarbonylamino)-5-imidazolecarboxamide (yield 65%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310070B1
Source datasetuspto-grants-2001_10
ORD IDord-3e4dce3662834bdf8a3f78918785cd9b
Source noteuspto-grants-2001_10