2-Fluorobenzoyl chloride → HCID 18360564, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 22, using 1.00 g (3.84 mmol) of 4-amino-1-(3-phenoxypropyl)-5-imidazolecarboxamide prepared in the same manner as in Example 156 and 2-fluorobenzoyl chloride instead of benzoyl chloride to obtain 1.35 g of 4-(2-fluorobenzoylamino)-1-(3-phenoxypropyl)-5-imidazolecarboxamide (yield 92%).

Provenance & Evidence