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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382552Generated: October 26, 2026

Cinnamoyl Chloride → (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole

https://huagongshe.com/reaction/382552

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCinnamoyl ChlorideHCID 5354261—
Reactant(E)-1-(2-pyridyl)-2-styryl-1H-benzimidazoleHCID 9796241—
Reactant1,2-Benzenediamine, N1-2-pyridinyl-4-(trifluoromethyl)-HCID 22736707—
Product(E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazoleHCID 22736704—

Reaction Steps

The titled compound was prepared from 2-amino-N-(2-pyridyl)-4-trifluoromethylaniline and (E)-cinnamoyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310079B1
Source datasetuspto-grants-2001_10
ORD IDord-f81d4b529a7d4793aef5f1ecaa676a38
Source noteuspto-grants-2001_10