HRID382588

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID971

Oxalic acid

C2H2O4

HCID13389

Pyridin-4-carboxaldehyde

C6H5NO

HCID22736643

2-Methyl-1-(pyridin-2-yl)-1H-benzimidazole

C13H11N3

$结构：C(=C\c1nc2ccccc2n1-c1ccccn1)/c1ccccn1.Cl.Cl$

HCID22736657

未命名化合物

PRODUCTS

生成物

$结构：C(=C\c1nc2ccccc2n1-c1ccccn1)/c1ccncc1.O=C(O)C(=O)O$

HCID22736688

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

Free base of the titled compound was prepared from 2-methyl-1-(2-pyridyl)-1H-benzimidazole and pyridine-4-carboxaldehyde according to the preparation of (E)-1-(2-pyridyl)-2-[2-(2-pyridyl)ethenyl]-1H-benzimidazole dihydrochloride (Example 44). The free base and oxalic acid were dissolved into MeOH. Concentration and recrystallization from ethyl MeOH/Et2O/n-hexane yielded the titled compound.

WORKUP

后处理

concentrationConcentration and recrystallization from ethyl MeOH/Et2O/n-hexane