Dichloromethane → HCID 131722915, compound

Participants

Reaction Steps

In the same manner as in Example 4-a) except that 98 mg of 4-nitrobenzyl (5R,6S)-2-(7-chloroimidazo[5,1-b]thiazol-2-yl)-6-((1R)-1-hydroxyethyl)-1-carbapen-2-em-3-carboxylate and a mixed solvent of dichloromethane and DMF (1:1), the crude 4-nitrobenzyl (5R,6S)-2-(7-chloro-6-methylimidazo[5,1-b]thiazolium-2-yl)-6-((1R)-1-hydroxyethyl)-1-carbapen-2-em-3-carboxylate iodide was obtained as a yellowish brown oil in a yield of 99 mg.

Provenance & Evidence