反应详情

温度

0 °C

35.4 g of octafluorotoluene (0.15 mol) are dissolved in 400 ml of dimethylformamide, the solution is cooled to 0° C. using a cryostat, and a solution of 40 g of potassium 4-benzyloxycarbonylphenoxide (0.15 mol) in 300 ml of dimethylformamide is then added drop wise over the course of 2 hours. After 24 hours at 0° C., the potassium salt has reacted. The dimethylformamide is then removed in a rotary evaporator, the residue is taken up in a little tetrahydrofuran, and the solution is filtered through a silica-gel column. The clear solution obtained is evaporated in a rotary evaporator until the reaction product precipitates out. The reaction product is then stirred in n-hexane, filtered off through a fluted filter and then dried for 48 hours under nitrogen at 40° C./10 mbar in a vacuum drying cabinet (yield: 95%).

1. customThe dimethylformamide is then removed in a rotary evaporator
2. filtrationthe solution is filtered through a silica-gel column
3. customThe clear solution obtained
4. customis evaporated in a rotary evaporator until the reaction product
5. customprecipitates out
6. filtrationfiltered off through
7. filtrationa fluted filter
8. customdried for 48 hours under nitrogen at 40° C./10 mbar in a vacuum
9. customdrying cabinet (yield: 95%)