Piconol → HCID 18361715, compound

Participants

Reaction Steps

The title-compound was prepared from 6-chloro-3-(4,5-dimethylisoxazol-3-yl)-1,2,4-triazolo[3,4-a]phthalazine prepared in Example 32 part a and 2-pyridylcarbinol using the procedure given for Example 1, 1H NMR (360 MHz, CDCl3) δ 2.30 (3H, s, Me), 2.49 (3H, s, Me), 5.73 (2H, s, CH2O), 7.29 (1H, m, Ar—H), 7.70-7.83 (3H, m, 3 of Ar—H), 7.96 (1H, m, Ar—H), 8.31 (1H, d, J=8.3 Hz, Ar—H, 8.64-8.70 (2H, m, 2 of Ar—H); MS (ES+) m/e 373 [MH]+; Anal. Found C, 64.38; H, 4.05; N,22.60. C20H16N6O2 requires C, 64.50; H, 4.33; N, 22.57%.

Provenance & Evidence