HRID383035

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13564

ETHANOL, 2-BROMO-, ACETATE

C4H7BrO2

结构：CC(=O)OCc1c(I)c(NC(=O)C(C)OC(C)=O)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I

HCID18429188

未命名化合物

PRODUCTS

生成物

结构：CC(=O)OCCN(C(=O)C(C)OC(C)=O)c1c(I)c(COC(C)=O)c(I)c(C(=O)NCC(COC(C)=O)OC(C)=O)c1I

HCID18429263

未命名化合物

收率 95%

PROCEDURE

实验过程

5-(2-Acetoxypropionylamino)-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamide was alkylated with 2-bromoethyl acetate according to the general procedure described in Example 25a. After work up the product was isolated in 95% yield.

WORKUP

后处理

customAfter work up the product was isolated in 95% yield

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b51268045d70438cb8b8a7b18ee9e5ce
来源数据集: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06310243B1
来源说明: uspto-grants-2001_10

反应 SMILES

[C:1]([O:4][CH:5]([CH3:37])[C:6]([NH:8][C:9]1[C:10]([I:36])=[C:11]([CH2:31][O:32][C:33](=[O:35])[CH3:34])[C:12]([I:30])=[C:13]([C:28]=1[I:29])[C:14]([NH:16][CH2:17][CH:18]([O:24][C:25](=[O:27])[CH3:26])[CH2:19][O:20][C:21](=[O:23])[CH3:22])=[O:15])=[O:7])(=[O:3])[CH3:2].[C:38]([O:41][CH2:42][CH2:43]Br)(=[O:40])[CH3:39]>>[C:38]([O:41][CH2:42][CH2:43][N:8]([C:6](=[O:7])[CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH3:37])[C:9]1[C:10]([I:36])=[C:11]([CH2:31][O:32][C:33](=[O:35])[CH3:34])[C:12]([I:30])=[C:13]([C:28]=1[I:29])[C:14]([NH:16][CH2:17][CH:18]([O:24][C:25](=[O:27])[CH3:26])[CH2:19][O:20][C:21](=[O:23])[CH3:22])=[O:15])(=[O:40])[CH3:39]